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Frames


Redundancy is a common tool in our daily lives. We double- and triple-check that we turned off gas and lights, took our keys, money, etc. (at least those worrywarts among us do). When an important date is coming up, we drive our loved ones crazy by confirming ``just once more'' they are on top of it. Of course, the reason we are doing that is to avoid a disaster by missing or forgetting something, not to drive our loved ones crazy.

 

The same idea of removing doubt is present in signal representations. Given a signal, we represent it in another system, typically a basis, where its characteristics are more readily apparent in the transform coefficients (for example, wavelet-based compression). However, these representations are typically nonredundant, and thus corruption or loss of transform coefficients can be fatal. In comes redundancy; we build a safety net into our representation so that we can avoid those fatal disasters. The redundant counterpart of a basis is called a frame.

 

It is generally acknowledged that frames were born in 1952 in the paper by Duffin and Schaeffer Despite being over half a century old, frames gained popularity only in the last decade, due mostly to the work of the three wavelet pioneers---Daubechies, Grossman and Meyer. Frame-like ideas, that is, building redundancy into a signal expansion, can be seen in pyramid coding, quantization, denoising, robust transmission, CDMA systems, multiantenna code design, segmentation, classification, prediction of epileptic seizures, restoration and enhancement, motion estimation, signal reconstruction, coding theory, operator theory and quantum theory and computing.

 

While frames are often associated with wavelet frames, it is important to remember that frames are more general than that.  Wavelet frames possess structure; frames are redundant representations that only need to represent signals in a given space with a certain amount of redundancy. The simplest frame is called the Mercedes-Benz (MB). The question now is: Why and where would one use frames? The answer is obvious: anywhere where redundancy is a must. The host of the applications mentioned above illustrates that richly.

 

We are concerned only with finite-dimensional frames. When we do venture into the infinite-dimensional one, we will do so only using filter banks---structured expansions used in applications. We will stay away from all other infinite-dimensional settings. Our current work is on constructing frame families for use in bioimaging.

Overview


Sponsor

This material is based upon work supported by the National Science Foundation under Grant No. 0515152.

Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the sponsor(s).

Collaborators

Amina Chebira, Stephen Lin, Yann Barbotin, Gowri Srinivasa, Charles Jackson, Markus Püschel, Pete Casazza, Matthew Fickus, John Ozolek, Carlos Castro

Research Corner

Frames in bioimaging

Frames in biometrics

Frames in robust transmission

Frames in a wireless environment

Frame families

Teaching Corner

Recent publications

Recent talks

Software

Multiresolution frame classification

Links

Under construction

Frames in bioimaging


General papers

A. Chebira and J. Kovačević, “Frames in bioimaging”, Proc. CISS, Princeton, NJ, Mar. 2008.

A. Chebira and J. Kovačević, “Adaptive multiresolution frame classification of biological and biometric images”, Proc. SPIE Conf. on Wavelet Applications in Signal and Image Processing, San Diego, USA, Aug. 2007.

A multiresolution approach to automated classification of protein subcellular location images

Background: The problem of automated interpretation of fluorescence microscope images depicting subcellular protein locations is at the forefront of the current trend in biology towards understanding the role and function of all proteins. Over the past ten years, the feasibility of using machine learning methods to recognize all major subcellular location patterns has been convincingly demonstrated, using diverse feature sets and combinations of classifiers.  On a well-studied data set of 2D HeLa single-cell images, the best performance to date, 91.5%, was obtained upon the addition of a simple set of multiresolution features.

 

Results: We report here a novel approach for the classification of subcellular location patterns by classifying in multiresolution subspaces. Our system is able to work with any feature set and any classifier. It consists of multiresolution (MR) decomposition, followed by feature computation and classification in each MR subspace, yielding local decisions that are then combined into a global decision.  With 26 texture features alone and a neural network classifier, we obtained an increase in accuracy on the 2D HeLa data set to 95.3%.

 

Conclusions: We demonstrate that the space-frequency localized information in the multiresolution subspaces adds significantly to the discriminative power of the system. Moreover, we show that a vastly reduced set of features is sufficient, consisting of our novel modified Haralick texture features. Our proposed system is general, allowing for any combinations of sets of features and any combination of classifiers.

A. Chebira, Y. Barbotin, C. Jackson, T. Merryman, G. Srinivasa, R. F. Murphy and J. Kovačević, “A multiresolution approach to automated classification of protein subcellular location images,” BMC Bioinformatics, vol. 8, no. 210, 2007. [rrc]

G. Srinivasa, T. Merryman, A. Chebira, A. Mintos and J. Kovačević, “Adaptive multiresolution techniques for subcellular protein location image classification”, Proc. IEEE Int. Conf. Acoust., Speech, and Signal Proc., Toulouse, France, May 2006, pp. V:1177-1180. Invited paper.

T. Merryman, K. Williams, G. Srinivasa, A. Chebira and J. Kovačević, “A multiresolution enhancement to generic classifiers of subcellular protein location images”, Proc. IEEE Intl. Symp. Biomed. Imaging, Arlington, VA, Apr. 2006, pp. 570-573.

Towards an image analysis toolbox for high-throughput Drosophila embryo RNAi screens

We build an image analysis toolbox for high-throughput Drosophila embryo RNAi screens. The goal is to tag the embryo as normal, developmentally delayed or abnormal based on the ventral furrow formation.  We break the problem into two parts: in the first, we detect the developmental stage based on the progress of the ventral furrow formation, and in the second, we tag the embryo as normal/developmentally delayed/abnormal based on the stage detected and the elapsed time. The crux of the algorithm is the multiresolution classifier, and we show that, by classifying in multiresolution spaces, we obtain better results than by classifying the embryo image alone. The final 2D accuracy obtained was 93.17%, while by using 3D information, it increased to 98.35%.

R. A. Kellogg, A. Chebira, A. Goyal, P. A. Cuadra, S. F. Zappe, J. S. Minden and J. Kovačević, “Towards an image analysis toolbox for high-throughput Drosophila embryo RNAi screens”, Proc. IEEE Intl. Symp. Biomed. Imaging, Arlington, VA, Apr. 2007, pp. 288-291.

Frame classification in histopathology

We propose a system for identification of germ layer components in teratomas derived from human and nonhuman primate embryonic stem cells.  Tissue regeneration and repair, drug testing and discovery, the cure of genetic and developmental syndromes all may rest on the understanding of the biology and behavior of embryonic stem (ES) cells.  Within the field of stem cell biology, an ES cell is not considered an ES cell until it can produce a teratoma tumor (the ``gold'' standard test); a seemingly disorganized mass of tissue derived from all three embryonic germ layers; ectoderm, mesoderm, and endoderm. Identification and quantification of tissue types within teratomas derived from ES cells may expand our knowledge of abnormal and normal developmental programming and the response of ES cells to genetic manipulation and/or toxic exposures.  In addition, because of the tissue complexity, identifying and quantifying the tissue is tedious and time consuming, but in turn the teratomas provides an excellent biological platform to test robust image analysis algorithms.  We use a multiresolution (MR) classification system with texture features, as well as develop novel nuclear texture features to recognize germ layer components. With redundant MR transform, we achieve a classification accuracy of approximately 88%.

A. Chebira, J. A.  Ozolek, C. A.  Castro, W. G.  Jenkinson, M. Gore, R. Bhagavatula, I. Khaimovich, S. E.  Ormon, C. S.  Navara, M. Sukhwani, K. E.  Orwig, A. Ben-Yehudah, G. Schatten, G. K.  Rohde and J. Kovačević, “Multiresolution identification of germ layer components in teratomas derived from human and nonhuman primate embryonic stem cells”, Proc. IEEE Intl. Symp. Biomed. Imaging, Paris, France, May 2008, pp. 979-982.

Frames in biometrics


An Adaptive Multiresolution Approach to Fingerprint Recognition

We propose an adaptive multiresolution (MR) approach to the classification of fingerprint images. The system adds MR decomposition in front of a generic classifier consisting of feature computation and classification in each MR subspace, yielding local decisions, which are then combined into a global decision using a weighting algorithm. In our previous work on classification of protein subcellular location images, we showed that the space-frequency localized information in the MR subspaces adds significantly to the discriminative power of the system. Here, we go one step farther; We develop a new weighting method which allows for the discriminative power of each subband to be expressed and examined within each class. This, in turn, allows us to evaluate the importance of the information contained within a specific subband. Moreover, we develop a pruning procedure to eliminate the subbands that do not contain useful information.  This leads to potential identification of the appropriate MR decomposition both on a per class basis and for a given dataset.  With this new approach, we make the system adaptive, flexible as well as more accurate and efficient.

A. Chebira, L. P. Coelho, A. Sandryhaila, S. Lin, G. W. Jenkinson, J. MacSleyne, C. Hoffman, P. Cuadra, C. Jackson, M. Püschel and J. Kovačević, "An adaptive multiresolution approach to fingerprint recognition", Proc. IEEE Conf. on Image Proc., San Antonio, TX, Sep. 2007, pp. I:457–460.

Wavelet packet correlation methods in biometrics

We introduce wavelet packet correlation filter classifiers. Correlation filters are traditionally designed in the image domain by minimization of some criterion function of the image training set. Instead, we perform classification in wavelet spaces that have training set representations that provide better solutions to the optimization problem in the filter design. We propose a pruning algorithm to find these wavelet spaces by using a correlation energy cost function, and we describe a match score fusion algorithm for applying the filters trained across the packet tree. The proposed classification algorithm is suitable for any object recognition task. We present results by implementing a biometric recognition system that uses the NIST 24 fingerprint database, and show that applying correlation filters in the wavelet domain results in considerable improvement of the standard correlation filter algorithm. We also motivate the use of frames in future work by demonstrating the effect of shift variance on recognition and identification accuracy.

P. Hennings Yeomans, J. Thornton, J. Kovačević and B.V.K.V. Kumar, "Wavelet packet correlation methods in biometrics'', Applied Optics, special issue on Biometric Recognition Systems, vol. 44, no. 5, February 2005., pp. 637-646.

J.T. Thornton, P. Hennings Yeomans, J. Kovačević and B.V.K.V. Kumar, ''Wavelet packet correlation methods in biometrics'', Proc. IEEE Int. Conf. Acoust., Speech, and Signal Proc., Philadelphia, PA, March 2005., pp. II:81-84.

 

Frames in robust transmission


Frame families robust to erasures

Motivated by the use of frames for robust transmission over the Internet, we present a first systematic construction of real tight frames with maximum robustness to erasures. We approach the problem in steps: we first construct maximally robust frames by using polynomial transforms. We then add tightness as an additional property with the help of orthogonal polynomials.  Finally, we impose the last requirement of equal norm and construct, to our best knowledge, the first real, tight, equal-norm frames maximally robust to erasures.

M. Püschel and J. Kovačević, ''Real, tight frames with maximal robustness to erasures'', Proc. Data Compr. Conf., Snowbird, UT, March 2005, pp. 63-72.

Quantized frame expansions with erasures

This work discusses frames in a new setting: when some of the elements are lost. Since some subsets of a redundant frame are themselves frames, a quantized frame expansion (QFE) can be a useful representation even when only a subset of the transform coefficients are available for computing a reconstruction. This yields robustness to losses in packet networks such as the Internet.

With a simple additive noise model for quantization, it is shown that a normalized frame minimizes mean-squared error (MSE) if and only if it is tight. With one quantized frame coefficient erased, a tight frame is again optimal among normalized frames, both in average and worse-case scenarios. For more erasures, a general analysis indicates some optimal designs.

V. K Goyal, J. Kovačević and J.A. Kelner, ''Quantized frame expansions with erasures'', Journal of Appl. and Comput. Harmonic Analysis, vol. 10, no. 3, May 2001, pp. 203-233.

V. K Goyal, J. Kovačević and M. Vetterli, ''Multiple description transform coding: Robustness to erasures using tight frame expansions'', Proc. IEEE Int. Symp. on Inform. Th., Boston, MA, August, 1998.

V. K Goyal, J. Kovačević and M. Vetterli, ''Quantized frame expansions as source-channel codes for erasure channels'', Proc. Wavelets and Appl. Workshop, Ticino, Switzerland, September 1998.

V. K Goyal, J. Kovačević and M. Vetterli, ''Quantized frame expansions as source-channel codes for erasure channels'', Proc. Data Compr. Conf., Snowbird, UT, March, 1999.

P.L. Dragotti, J. Kovačević and V. K Goyal, ''Quantized oversampled filter banks with erasures'', Proc. Data Compr. Conf., Snowbird, UT, March, 2001, pp. 173-182.

Filter bank frame expansions with erasures

The frames we started with are finite dimensional. Due to their practical importance, we decided to investigate those in l2(Z) implementable by filter banks. The paper below analyzes the system in parallel: for finite-dimensional spaces and l2(Z). We found that any equal-norm tight frame is optimal when no erasures are present. When there is one erasure, we know that any oversampled filter bank which implements a strongly equal-norm tight frame is robust to one erasure and minimizes the MSE. When there are e>1 erasures, depending on whether e is smaller or larger then N, the minimum occurs when the erased elements are either orthogonal or form a tight frame.

J. Kovačević, P.L. Dragotti and V. K Goyal, ''Filter bank frame expansions with erasures'', IEEE Trans. Inform. Th., special issue in Honor of Aaron D. Wyner, vol. 48, no. 6, June 2002, pp. 1439-1450. Invited paper.

P.L. Dragotti, J. Kovačević and V. K Goyal, ''Quantized oversampled filter banks with erasures'', Proc. Data Compr. Conf., Snowbird, UT, March 2001, pp. 173-182.

 

Frames in a wireless environment


Quantized frame expansions in a wireless environment

Here, we study frames for robust transmission over a multiple-antenna wireless system - BLAST. By considering as erased a component received with an SNR inferior to a given threshold, we place frames in a setting where some of the elements are deleted. In ``Quantized frame expansions with erasures'', we focused on the performance of quantized frame expansions up to M-N erased components, the structure of a frame being thus preserved. In this work we consider every possible scenario of erasures for low-dimensional frames and we present optimal designs for corresponding systems using a small number of antennas.

A. C. Lozano, J. Kovačević and M Andrews, ''Quantized frame expansions in a wireless environment'', Proc. Data Compr. Conf., Snowbird, UT, March 2002, pp. 480-489.

A. C. Lozano, J. Kovačević and M Andrews, ''Quantized frame expansions in a wireless environment'', Proc. DIMACS Workshop on Source Coding and Harmonic Analysis, Rutgers, NJ, May 2002.

 

Frame families


Lapped tight frame transforms

We propose a new class of equal-norm tight frames termed Lapped Tight Frame Transforms (LTFTs).  These can be seen as a redundant counterpart to bases known as Lapped Orthogonal Transforms (LOTs) introduced by Malvar and Cassereau, as well as an infinite-dimensional counterpart to Harmonic Tight Frames (HTFs). To construct LTFTs, we seed them from LOTs and show that, in a specific case, the process preserves the equal norm. As both their basis counterpart LOTs as well as their finite-dimensional one HTFs, LTFTs possess many desirable properties, such as equal norm and efficient implementation.

A. Chebira and J. Kovačević, “Lapped tight frame transforms”, Proc. IEEE Int. Conf. Acoust., Speech, and Signal Proc., Toronto, Honolulu, HI, Apr. 2007, pp. III:857-860.

Physical interpretation of finite tight frames

We find finite tight frames when the lengths of the frame elements are predetermined. In particular, we derive a ``fundamental inequality" which completely characterizes those sequences which arise as the lengths of a tight frame's elements. Furthermore, using concepts from classical physics, we show that this characterization has an intuitive physical interpretation.

P.G. Casazza, M. Fickus, J. Kovačević, M. Leon and J. Tremain, ''A physical interpretation of finite tight frames'', Harmonic Analysis and Applications, C. Heil, Ed., Birkhauser, Boston, MA, 2006.

Equal-norm tight frames with erasures

Since equal-norm tight frames have been shown to be useful for robust data transmission, we give the first systematic study of the general class of equal-norm tight frames and their properties. We search for efficient constructions of such frames. We show that the only equal-norm tight frames with the group structure and one or two generators are the generalized harmonic frames. Finally, we give a complete classification of frames in terms of their robustness to erasures.

P.G. Casazza and J. Kovačević, ''Equal-norm tight frames with erasures'', Advances in Computational Mathematics, special issue on Frames, 2002. Invited paper.

P.G. Casazza and J. Kovačević, ''Uniform tight frames for signal processing and communications'', Proc. SPIE Conf. on Wavelet Appl. in Signal and Image Proc., San Diego, CA, July 2001.

 

Recent publications


J. Kovačević and A. Chebira, An Introduction to Frames, Foundations and Trends in Signal Processing, Now Publishers, 2008.

J. Kovačević and A. Chebira, “Life beyond bases: The advent of frames (Part II)”, IEEE SP Mag., vol. 24, no. 5, Sep. 2007, pp. 115-125. Feature article.

J. Kovačević and A. Chebira, “Life beyond bases: The advent of frames (Part I)”, IEEE SP Mag., vol. 24, no. 4, Jul. 2007, pp. 86-104. Feature article.

A. Chebira, Y. Barbotin, C. Jackson, T. Merryman, G. Srinivasa, R. F. Murphy and J. Kovačević, “A multiresolution approach to automated classification of protein subcellular location images,” BMC Bioinformatics, vol. 8, no. 210, 2007. [rrc]

P.G. Casazza, M. Fickus, J. Kovačević, M. Leon and J. Tremain, ''A physical interpretation of finite tight frames'', Harmonic Analysis and Applications, C. Heil, Ed., Birkhauser, Boston, MA, 2006.

M. Püschel and J. Kovačević, ''Real, tight frames with maximal robustness to erasures'', Proc. Data Compr. Conf., Snowbird, UT, March 2005, pp. 63-72.

 

Recent talks


Real, tight frames with maximal robustness to erasures

Frames and applications

Links


Under construction