Feedback for Multiple Choice Quiz 10
- Limited digestion of an IgG molecule by papain results in selective cleavage at the neck of the "Y-shaped" molecule. See Fig. 14.23 for a diagram of the IgG molecule, but where the Fab and Fc portions are not identified!
- These are all important structural features of antibodies.
- The immunoglobulin fold is a supersecondary structure found in many proteins. It is found no less than 12 times in the IgG molecule.
- Fig. 14.23 does show this feature of the IgG molecule.
- The production of monoclonal antibodies is diagrammed in Fig. 14.26 where it is shown that mouse "cancer patients" are used.
- Antibodies can be selected to bind almost anything, but in nature the largest number of different epitopes result from the diverse surfaces of proteins.
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