| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Grade Distribution |
0 | 1 |
  |
20 | 4 |
  |
40 | 15 |
  |
60 | 32 |
  |
80 | 55 |
  |
100 | 26 |
  |
  |
Glycolysis
(-1) no answer
(1) does not require O2 to generate energy
(2) requires O2 to generate energy
(3) is inhibited by O2
(4) rate is increased in the presence of O2
|
-1 | 0 |
1 | 26 | |
2 | 3 | |
3 | 1 | |
4 | 3 | |
In humans, pyruvate can be converted to
(-1) no answer
(1) acetyl-CoA only
(2) lactate only
(3) ethanol only
(4) acetyl-CoA and lactate
|
-1 | 0 |
1 | 3 | |
2 | 5 | |
3 | 0 |
4 | 22 | |
Which statement best characterizes the role of enzymes in glycolysis?
(-1) no answer
(1) Several steps do not require enzymes
(2) Several steps are catalyzed by a single multifunctional enzyme
(3) One multifunctional enzyme catalyzes the whole pathway
(4) Each step is catalyzed by a separate enzyme
|
-1 | 0 |
1 | 0 |
2 | 4 | |
3 | 0 |
4 | 20 | |
The binding of glucose to hexokinase
(-1) no answer
(1) The binding of is an example of lock-and-key binding of a substrate to the active site of an
enzyme
(2) involves a large conformational change in the enzyme
(3) differs from the binding of substrates to other kinases
(4) is not well characterized
|
-1 | 0 |
1 | 3 | |
2 | 25 | |
3 | 0 |
4 | 1 | |
The reduction of pyruvate to lactate
(-1) no answer
(1) allows for recycling of NAD+
(2) is the process that aids in the recovery of sore muscles after exercise
(3) is accompanied by phosphorylation of ADP
(4) does not occur in aerobic organisms
|
-1 | 0 |
1 | 23 | |
2 | 0 |
3 | 1 | |
4 | 3 | |
Alcohol dehydrogenase resembles lactate dehydrogenase in that it
(-1) no answer
(1) is nonallosteric
(2) is a dimer
(3) uses NAD+ as a coenzyme
(4) is not found in aerobic organisms
|
-1 | 0 |
1 | 3 | |
2 | 0 |
3 | 21 | |
4 | 1 | |
The enzyme glucokinase
(-1) no answer
(1) phosphorylates a number of different sugars, including glucose, fructose, and
mannose
(2) specifically phosphorylates glucose rather than other sugars
(3) is the only kinase involved in glycolysis
(4) none of these are correct
|
-1 | 0 |
1 | 0 |
2 | 25 | |
3 | 0 |
4 | 2 | |
Redox reactions of NADH-linked dehydrogenases involve
(-1) no answer
(1) hydride ion transfer
(2) transfer of two-carbon groups
(3) transfer of three-carbon groups
(4) transfer of acetyl groups
|
-1 | 0 |
1 | 26 | |
2 | 2 | |
3 | 3 | |
4 | 4 | |
If glycolysis did not lead to the production of ATP, the overall process would
(-1) no answer
(1) release less energy
(2) release more energy
(3) absorb energy
(4) not take place in aerobic organisms
|
-1 | 0 |
1 | 6 | |
2 | 13 | |
3 | 10 | |
4 | 3 | |
Which of the following proteins resembles 'PACMAN' in its shape as well as function?
(-1) no answer
(1) myoglobin
(2) hexokinase
(3) hemoglobin
(4) collagen
|
-1 | 0 |
1 | 0 |
2 | 24 | |
3 | 0 |
4 | 0 |
The phosphorylation of glucose to glucose 6-phosphate (G-6-P)
(-1) no answer
(1) is so strongly exergonic that it does not require a catalyst
(2) is an exergonic reaction not coupled to any other reaction
(3) is an endergonic reaction that takes place because it is coupled to the
exergonic hydrolysis of ATP
(4) is an exergonic reaction that is coupled to the endergonic hydrolysis of ATP
|
-1 | 0 |
1 | 0 |
2 | 1 | |
3 | 28 | |
4 | 4 | |
The step that commits the cell to metabolize glucose is catalyzed by
(-1) no answer
(1) hexokinase
(2) phosphoglucomutase
(3) aldolase
(4) phosphofructokinase
|
-1 | 0 |
1 | 11 | |
2 | 0 |
3 | 0 |
4 | 19 | |
The conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate is
(-1) no answer
(1) a strongly endergonic reaction
(2) accompanied by a dehydration of the molecule
(3) one of the reactions of glycolysis in which ATP is produced
(4) a side reaction not part of the main pathway of glycolysis
|
-1 | 0 |
1 | 3 | |
2 | 1 | |
3 | 20 | |
4 | 1 | |
The conversion of 2-phosphoglycerate to phosphoenolpyruvate is
(-1) no answer
(1) an oxidation
(2) a reduction
(3) an isomerization
(4) a dehydration
|
-1 | 0 |
1 | 0 |
2 | 0 |
3 | 0 |
4 | 25 | |
The phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate is
the committed step in glycolysis because
(-1) no answer
(1) it is the rate-limiting step
(2) it is the most strongly exergonic step in the pathway
(3) fructose 1,6-bisphosphate can undergo no other reactions than those of
glycolysis
(4) two phosphate groups are involved
|
-1 | 0 |
1 | 6 | |
2 | 6 | |
3 | 43 | |
4 | 0 |
Which of the following exercise(s) allosteric control in the reaction of
phosphofructokinase?
(-1) no answer
(1) ATP
(2) fructose 2,6-bisphosphate
(3) both of these compounds
(4) neither of these compounds
|
-1 | 0 |
1 | 15 | |
2 | 0 |
3 | 34 | |
4 | 4 | |
An enzyme not involved in the control of glycolysis is
(-1) no answer
(1) hexokinase
(2) triose phosphate isomerase
(3) pyruvate kinase
(4) phosphofructokinase
|
-1 | 0 |
1 | 1 | |
2 | 40 | |
3 | 15 | |
4 | 0 |
Which of the following statements is true?
(-1) no answer
(1) All allosteric proteins are oligomeric
(2) All proteins that show cooperative binding are oligomeric
(3) all proteins that show non-cooperative binding are monomeric
(4) none of these statements are true.
|
-1 | 0 |
1 | 13 | |
2 | 20 | |
3 | 2 | |
4 | 19 | |
Under conditions of high [ATP], phosphofructokinase shows which of the following behaviour?
(-1) no answer
(1) Non-cooperative
(2) Negative cooperativity
(3) Positive cooperativity
(4) Childish.
|
-1 | 0 |
1 | 0 |
2 | 26 | |
3 | 22 | |
4 | 0 |