Gattaca is a cool, stylish thriller set in a society
where people have come to believe that DNA is destiny - that our futures can be
mapped out in our genes. There is certainly precedent for that: no less a person
than Jim Watson, the co-discoverer ofthe double helix of DNA itself, told Time
magazine in 1989, "We used to think our destiny was in the stars. Now we know
it's in our genes."
Into this society comes an impostor, Vincent Freeman, whose life ambition is
to travel into space on a mission to Titan, the largest of Saturn' s moons. But
Vincent was conceived in the American way, in the back seat of a car, and the
roll of the DNAdice has left him short of the genetic
gold standard required of astronauts. No efforts he can make by
himself will remove the modern marks of Cain.
By the time of his younger brother, however, their parents' passion is under
control and they conceive lots of embryos by in-vitro fertilisation (IVF),
selecting only the genetically most healthy for implantation into the mother's
womb. Gattaca is aworld of designer babies, achieved not
by sophisticated genetic engineering, but by a plausible
extension of what is already being practiced. In Britain today, some embryos
conceived through IVF are already having their genes checked and
selectivelyimplanted. This pre-implantation diagnosis is being carried out under
strict regulation (in this country at least) and for the most honourable of
motives. Some mothers at risk of having boys with the devastating
genetic disorder Duchenne MuscularDystrophy have elected
to have only female embryos implanted because the disorder, like haemophilia, is
expressed only in males.
But in a little noticed speech just before Christmas, one of this country's
outstanding geneticists, Professor Peter Goodfellow, told a meeting of the
Genetic Interest Group (the support organisation for
families with genetic disorders) that it might
bepossible within 20 years to read out not just a few disease-related genes
during pre- implantation diagnosis, but an embryo's entire genetic
make-up - blue eyes, fair hair, the lot. And not only would it be
possible, it would be cheap. Science, it wouldappear, will imitate art.
In the film, to subvert the system and realise his ambition to "slip the
surly bonds of Earth to touch the face of God", Vincent colludes with a champion
athlete, Jerome, to use samples of Jerome's DNA to deceive the oppressive and
all-pervasiveidentity checks. Vincent wears a pad containing Jerome's blood on
his forefinger to beat the entry system to the space headquarters. Staff have to
pass daily through turnstiles that automatically take a minute blood sample from
a finger- prick andproduce a DNA-fingerprint to check identity.
Here, art is imitating politics. In July 1996, Frank Field, now junior
minister in the Department of Social Security, wrote a polemic in the Sunday
Mirror advocating that benefits claimants should be genetically fingerprinted so
as to avoid socialsecurity fraud: "Your number's up! Why DNA testing can beat
the welfare cheats".
Jerome was born with all the best genes, but they did not protect him from a
road accident that left him crippled, wheelchair-bound, and without a role in
this brave new world. He fulfils his destiny vicariously by selling his
genetic samples to Vincentwho officially becomes Jerome
(who retreats to use his middle name, Eugene - a pun on eugenics meaning "well-
born"). The name's hand-over is symbolic (Jerome means "sacred name") and the
film's title too is a pun, deriving from the four key chemicalsin DNA - guanine,
adenine, thymine, and cystosine - whose acronym spells GTCA.
As the relationship between Vincent/Jerome and Jerome/Eugene grows beyond a
mercantile one, questions of identity arise. In a society based on
genetics, who is the real Jerome? The individual who
passes through the turnstile every morning or the manwhose DNA profile passes
the turnstiles? And what happens to sexual relationships in such a society? In
one scene, people queue up to have DNA samples analysed - single strands of hair
from potential lovers and partners - including one woman who has herlips swabbed
to analyse the DNA of the man she kissed 20 minutes earlier, to see if she
should take the relationship any further. Another nice touch is the helical
staircase in the apartment shared by Vincent/Jerome and Jerome/Eugene.
Genes are not destiny, but they could become so if everyone starts believing
that they are. Anyone who thinks the mindset of the world of Gattaca
a tad implausible should turn to the excellent little book, The DNA
Mystique - the gene as a cultural iconby the American sociologists of science
Dorothy Nelkin and Susan Lindee. For page after page after page, they catalogue
the obsession that contemporary culture has with genes and DNA.
Gattaca is a modern morality play on the errors of
genetic
determinism. Equally we should
avoid the trap of technological determinism - of
thinking that such a stylish but oppressive future is inevitable. For the truth
is that such consequences aredependent not only on the scientific research but
also upon the public policy response of society. If we ordered society
differently then we could have the benefits of gene discovery - freedom from the
suffering imposed by genetic disease - without
thedemerits portrayed in this film.
Does making this society's problem absolve the geneticists of responsibility?
It is unreasonable, in my view, to expect scientists whose expertise may be in,
say, molecular biology also to have the expertise in the historical and social
sciencesnecessary to form a judgement about the wider consequences of their
research. Some may wish to express a view as concerned individual citizens; some
may not.
But that is not the end of the matter. Next week, the Wellcome Trust will
announce a programme to spend pounds 15m over the next five years examining the
sorts of issues raised fictionally by Gattaca. Half the
money will go on bringing such ethicalissues to public attention. Two plays for
secondary schools have already piloted the initiative: The Gift, on
genetics; and Cracked on mental health.
The rest will go on research into the social and public policy consequences
of biomedical advance, including understanding public attitudes and the values
that inform public judgements on moral acceptability. The outputs of this
research programmeshould help inform decision-makers at all levels about the
appropriate policies to pursue in the light of developments in the laboratories
and hospital clinics.
Most of the recent controversial scientific discoveries - Dolly for example -
were the fruits of years of scientific research. Exploring their implications
for society merits as serious an effort in social and policy research, rather
than sound-bitesand media punditry. That research may not lead to "the" answer,
but it will map out some possible futures. Then it is up to society to
decide.
And as for my genetic defect? That is a matter for me
and my family. We do not live in the world of Gattaca.
Yet.
Dr Tom Wilkie heads the biomedical ethics section at the Wellcome
Trust.
Tom Wilkie, We have ways to make sure that your genes become your destiny. , Independent, 03-21-1998, pp 23.