Biochemistry I - Effect of pH on Protonation - Monofluoroacetic Acid

You are varying the pH of a solution of monofluoroacetic acid (by adding HCl or NaOH) and measuring the fraction of the acid is protonated. (Note that the pKa of the acid has been rounded to the nearest integer.)
  1. Enter a pH, from pH=1 to 8, in steps of 0.5, and obtain the fraction protonated at that pH.
  2. Plot fraction protonated versus pH.
1. Enter a value for pH in this box:
pH =
2. For the above value of pH, the fHA is:
fHA =
    (Each measured value has a small "experimental error" added to it.)


Jan 2024