Biochemistry I Fall Term, 2005

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Quiz on Lecture 32: Integrated Metabolism
1. Regulated metabolic pathways are:
irreversible.
committed after the first step.
usually regulated at the first step.
compartmentalized in eukaryotes.
All of the above are correct.
2. Each reaction in a metabolic pathway is:
controlled by the end product.
catalyzed by a specific enzyme.
irreversible.
reversible.
linked to at least two other pathways.
3. The hormones, glucagon and epinephrine, stimulate glycogen breakdown to G-6-P
directly, by binding to glycogen phosphorylase.
indirectly, by first stimulating adenylate cyclase to make cAMP.
only in the liver.
only in muscle cells.
using ATP as the phosphoryl donor.
4. Activation of the ___ kinase results in the activation of ___ kinase and thereby the phosphorylation of both glycogen phosphorylase and glycogen synthase.
pyruvate, phosphorylase
phosphorylase, cAMP-dependent protein
cAMP-dependent protein, phosphorylase
cAMP-dependent protein, pyruvate
None of the above.
5. When it functions as a "second messenger", cAMP
acts outside the cell to influence cellular processes.
acts "second in importance" to AMP.
activates all cytosolic protein kinases.
activates the cAMP-dependent protein kinase.
binds to calmodulin causing it to bind Ca2+.
6. The major free energy sources for anabolic pathways are:
ATP and NADPH.
ATP and NADP+.
ADP and NADPH.
ADP and NADP+.
AMP or NADPH.
7. Which of the following compounds is responsible for coordinated regulation of glucose and glycogen metabolism?
NADH
NAD+
acetyl-CoA
fructose 2,6 bis-phosphate
fructose 1,6 bis-phosphate
8. Opposing degradative and biosynthetic pathways
use the same enzymes for many steps.
use different enzymes for steps that require large energy changes.
are coordinately regulated at the steps that use different enzymes.
are used in both directions in most organisms.
all of the above
 

 

 

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Lecture 32: Integrated Metabolism.