PERSONNEL

Jonathan Minden Associate Professor Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 minden@cmu.edu

Education

Ph.D., Albert Einstein College of Medicine
Postdoctoral Appointment, University of California, San Francisco
Lucille P. Markey Charitable Trust Scholarship

Research

My lab uses molecular genetics and high end optical microscopy to investigate pattern repair during Drosophila embryogenesis. We are also developing new genomic, proteomic, and imaging technologies to assay qualitative and quantitative changes in gene expression. (more)

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Susan Dowd Research Associate Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 sd2k@andrew.cmu.edu

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Mamta Puri Graduate Student Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 mpuri@andrew.cmu.edu

Education

B.Sc. Life Sciences and Biochemistry, St. Xavier's College, Bombay, India
M.Sc. Biotechnology, M.S.University, Baroda, India

Research

Gastrulation in Drosophila involves a number of cell shape changes, the first of which is the formation of the ventral furrow, which eventually leads to the formation of the mesoderm. The process of ventral furrow formation takes only about 15 minutes. The idea that the proteasome plays a key role in this process stems from the observations that analysis of the difference-proteins between ventralized versus lateralized embryos resulted in identification of three proteasomal subunits, as well as the result that ventral furrow formation seems to be inhibited on introduction of a proteasomal inhibitor, lactacystin. I am interested in understanding the role of the proteasome in affecting cell shape changes during gastrulation in Drosophila.

Anupam Goyal Graduate Student Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 anupamg@andrew.cmu.edu

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FORMER LAB MEMBERS

Katherine Robertson Postdoctoral Research Associate Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 kr3@andrew.cmu.edu

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Jaime Mergliano Postdoctoral Research Associate Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 taffy@andrew.cmu.edu

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Lei Gong Research Assistant Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 leig@andrew.cmu.edu

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Surya Viswanathan Graduate Student Department of Biological Sciences Mellon Institute, Room 281, Pittsburgh, PA 15213 412-268-3448 suryav@andrew.cmu.edu

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