This course has two sections: The first half of the course covers microbial physiology and metabolism, fermentation and restoration, metabolic regulation, bioconversions, recombinant DNA methodology and gene cloning. The second half of the course covers separation and purification, kinetcs, and design of biological reactors, mass transfer limitations within cell suspensions, and control of fermentation processes. This course meets concurrently with 42-721/06-721. Prerequisites: 03-121 Modern Biology OR 03-231/03-232 Biochemistry AND 06-262 Math. Methods of Chemical Engineering OR 21-260 Differential Equations OR permission of instructor.