This course will cover all aspects of analytical instrumentation and its application to problems in materials, environmental, and biological chemistry. Topics covered will include chromatographic separations, mass spectrometry, optical spectroscopies, electrochemistry, optical and force microscopies and potentially NMR. In addition, the course will emphasize how to select an analytical method appropriate to the problem at hand, how to optimize the signal to noise obtained by a measurement, and the quantitative analysis of experimental data. 3 hrs. lec.