This is Part I of a two-part course sequence in Biomaterials. This introductory course will address basic and applied concepts of polymers as biomaterials. The students will be exposed to both fundamental synthetic mechanisms of polymers and their physical and chemical properties. Specific emphasis will be placed on biodegradation mechanisms, mechanical properties, and surface chemistry of polymeric materials. Cellular interactions with various surfaces and immunological responses will be covered. Applications of biomaterials to be discussed include tissue engineering and artificial organs. Part II of this course will be offered in the fall and the focus will be on the principles, properties and applications of ceramics and metals as biomaterials.